Randomized Controlled Trial of Stress Reduction with Meditation and Health Education in Black Men and Women with Normal and Elevated Blood Pressure

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Am J Prev Cardiol. October 4, 2021; 8: 100279. doi: 10.1016 / j.ajpc.2021.100279. eCollection 2021 Dec.

ABSTRACT

BACKGROUND: Black men and women suffer from disparities in morbidity and mortality from hypertension, cardiovascular disease, and currently COVID-19. These conditions are associated with social determinants of health and psychosocial stress. While previous trials have shown that reducing stress with meditation lowered BP to the grade I range in black adults, there is little evidence of high normal and normal BP.

OBJECTIVE: This randomized controlled trial was conducted to evaluate the effect of stress reduction with the Transcendental Meditation (TM) technique in black adults with high normal BP and normal BP using international classifications.

METHODS: A total of 304 black men and women with high normal (130-139 / 85-89 mm Hg) and normal (120-129 / 80-84 mm Hg) blood pressure were randomized to the TM or education groups. health (HE). . BP was recorded at 3, 6, 9, 12, 24, 30 and 36 months after inclusion. A linear mixed model analysis was performed to compare the change in BP between participants TM and HE in the high normal PA and normal PA groups. Survival analysis for hypertensive events was performed.

RESULTS: After a mean follow-up of 19.9 ± 11.1 months, MT participants in the high normal PA group had a significantly lower post-test SBP (-3.33 mm Hg, p = 0.045). There was no difference in DBP (-0.785 mm Hg, p = 0.367) compared to ES participants. In the normal BP group, SBP and DBP were not different between the TM and HE participants. The hazard ratio for hypertensive events was 0.52 (p = 0.15) in the high normal PA group (7 MT vs 13 EO) without difference in the normal PA group.

CONCLUSION: This RCT found that meditation reduced systolic BP in black men and women with high normal BP, but not in participants with normal BP. These findings may be relevant in reducing health disparities in cardiovascular disease and associated comorbidities.

IDPM: 34729544 | PMC: PMC8546372 | DOI: 10.1016 / j.ajpc.2021.100279

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